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Criticality and Hierarchy of Temporal Dynamics in the Human Brain

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The human brain is a complex dynamic system whose activity unfolds across multiple temporal scales. Two fundamental properties capture this temporal organization: criticality, which reflects how the system operates at the balance between stability and flexibility, and the hierarchy of intrinsic neural timescales, ranging from rapid sensory responses to slow integrative processes. These dynamical properties support efficient information processing, flexible state transitions, and the integration of information across spatial and temporal scales. However, it remains unclear how alterations in brain structure affect these properties and the functions they enable. In this seminar, we will introduce these two key dynamical features and investigate how they are altered in the context of aging and stroke. By combining multimodal neuroimaging with computational modelling, we characterise how structural changes associated with aging and focal lesions shift the brain’s critical state and reshape the temporal hierarchy across different age groups and following stroke. This integrated framework reveals systematic reorganization of large-scale brain dynamics across healthy aging and post-stroke recovery.


This IFISC Seminar will be broadcasted in the following zoom link: https://us06web.zoom.us/j/89027654460?pwd=Wg9TYMPqqP2ipfj2JVvEagmzaTw29c.1


Coffee and cookies will be served 15 minutes before the start of the seminar


Detalls de contacte:

Claudio Mirasso

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