The effect of noise and heterogeneity is studied in a multi-neuron
generalization of a two-neuron model of wake-sleep cycle introduced
recently [S. Postnova, K. Voigt, H.A. Braun, J. Biol. Rhythms 24, 523
(2009)]. This minimal but physiologically plausible two-neuron model
introduced a mechanism of homeostatic regulation of sleep based on
Orexin/Hypocretin, a co-transmitter of the lateral hypothalamus, and on
Glutamate.
It is shown that in the presence of an external periodic signal,
representing e.g. a daily light stimulus or a circadian cycle, there are
suitable levels of heterogeneity of the neuronal couplings or of the
noise currents that are optimal for the system response to the external
stimulus.
Coffee and cookies will be served 15 minutes before the start of the seminar
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