presentation/307 1st BioSim Conference - Presentation

1st BioSim Conference


Course: Introduction to CellML and COR

Author: Anna Sher, Oxford University.

Names and affiliation of other authors:

Oral or poster: Oral presentation

Computer models in cardiac electrophysiology have proven to be extremely valuable to both experimental and theoretical research.Several environments have been developed over the last two decades to facilitate the creation and use of such models. There has always been an issue with the exchange of models due to errors being introduced when publishing a model and when implementing someone´s model.
This issue in recent years has been the subject of increasing concern and has,among other efforts, resulted in the release of CellML,which is primarily used for mathematically describing any (sub-)cellular biological process and facilitating the exchange of models.It is an open standard based on the XML markup language(see,which makes use of MathML for describing the mathematics (see RDF for incorporating metadata (see
Since the release of CellML,different teams have been developing new or improving existing modelling environments to support CellML.One such new environment is Cellular Open Resource (COR;,the emphasis of which is on the creation and use of cardiac cellular electrophysiological models in either a research or a teaching context.Because of its CellML capability,COR offers indirect access to an increasing number of cellular models.
This talk will follow the above structure,giving an overview of CellML and then of COR,together with a live demonstration of the soft.

1st BioSim Conference. October 6th to October 8th, 2005. Palma de Mallorca, Spain.