presentation/200 1st BioSim Conference - Presentation

1st BioSim Conference

Presentation

Dynamics robustness of cellular function

Author: FJ Bruggeman, Molecular Cell Physiology, Vrije universiteit, Amsterdam, 2. Manchester Centre for Integrative Systems Biology , Manchester I.

Names and affiliation of other authors:
HV Westerhoff
1. Molecular Cell Physiology, Vrije universiteit, Amsterdam, The Netherlands
2. Manchester Centre for Integrative Systems Biology
Manchester Interdisciplinary Biocentre (MIB)
University of Manchester
Manchester, United Kingdom

Oral or poster: Oral presentation

Abstract:
Cells in general, and unicellular organisms in particular, are continously challenged by changes in their environment. Those changes can be beneficial, or hazardous. Often cells respond by adapting their physiology in such a way that some of its functions change while some remain invariant. The latter functions are then robust whereas the former ones are fragile. I will introduce methods to analyze and explain robustness in terms of the network topology and its dynamic organization.

1st BioSim Conference. October 6th to October 8th, 2005. Palma de Mallorca, Spain.