A new approach to sensitivity analysis, parameter reduction and experimental optimisation for cellular network dynamics.
Author: David Rand, University of Warwick.
Names and affiliation of other authors:
Oral or poster: Oral presentation
Abstract: I develop a more global approach to sensitivity analysis that studies the variation of the whole solution rather that focusing on just one output variable. The mathematical basis is the local geometric rigidity of such systems. This leads to new approaches to parameter reduction and experimental optimisation enabling prediction of which experimental protocols and perturbations best reveal which aspects of the system and a cost-benefit analysis of the different possibilities for data collection