presentation/195 1st BioSim Conference - Presentation

1st BioSim Conference


Modelling circadian rhythm with tumour growth

Author: Jean Clairambault, INRIA & INSERM.

Names and affiliation of other authors:

Oral or poster: Oral presentation

The circadian clock controls the cell division cycle phase transitions in proliferating tissues by modulating cyclins and cyclin dependent kinases (CDKs), until effective division. Modelling relies on age-structured partial differential equations for cell proliferation, and on ordinary differential equations for the control of phase transitions and for the circadian clock described as a network of oscillators. The output of the controlled cell proliferation model is a population growth exponent.

1st BioSim Conference. October 6th to October 8th, 2005. Palma de Mallorca, Spain.